Insulin
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Researchers have converted stomach stem cells into insulin-producing cells that respond to changes in blood glucose levels. The discovery could mean that one day, diabetics produce their own insulin instead of relying on injections.
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Australian scientists have designed a new capsule that could mean diabetics might one day swallow their insulin instead of injecting it. The design also has potential uses in delivering other protein drugs, such as antibiotics and cancer treatments.
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For type 1 diabetics, it's imperative that they maintain healthy blood glucose levels to avoid complications. Researchers have developed a self-adjusting nanoparticle-based insulin that may go some way towards improving blood glucose control.
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Bariatric surgery has proven successful at treating obesity and reversing diabetes, but it's not without risks. Working with rodents, researchers have found a way to harness benefits similar to those from surgery, but in the form of an injection.
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A phase 2 clinical trial is currently exploring a new technique to slow the progression of type 2 diabetes. The simple outpatient surgery can be conducted in the early stages of diagnosis and delay the need for insulin shots.
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It’s long been thought that migraine and blood sugar level issues have been related, but now scientists have identified that they're genetically linked, opening the door for novel therapies and even prevention strategies for sufferers.
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With the incidence of type 2 diabetes on the rise, science is looking to genetics for answers. A new study has isolated a gene not previously associated with the disease that appears to impair insulin production in type 2 diabetics.
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A large-scale genetic analysis has revealed microRNAs in human pancreatic cells strongly associated with type 2 diabetes (T2D). The results can be used in future research into how the condition develops and how it can best be detected and treated.
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In an ideal world, managing diabetes wouldn’t involve insulin injections but just popping a pill. Now a team of scientists has demonstrated an oral tablet that’s self-propelled by chemical “micromotors” to deliver insulin in the colon of rats.
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While islet cell transplants allow some diabetics to forgo daily insulin injections, those people must take immunosuppressive drugs to protect those cells. A new implant, however, could administer the drugs for them, with fewer side effects.
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Scientists in Australia have opened up some new possibilities around oral insulin, by identifying a molecule that activates receptors in a similar way to the hormone, thereby laying new foundations to explore digestible drugs that mimic its effects.
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Stanford researchers have created a functional cure for diabetes in mice, by giving them a hybrid immune system. Treated animals were able to manage their blood glucose levels for the duration of the trial, without needing immune suppressants.
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